My research program is aimed at achieving a better understanding of childhood development and the consequences of early brain injury. We use several methodological and technological approaches in four main spheres of investigation:

• Studies of normal childhood development and predictive factors of brain and cognitive maturation
• Investigation of the effects of perinatal brain injury (e.g. prematurity) and postnatal brain injury (e.g. cranial trauma) on cognition, social competence, quality of life and brain development
• Development and validation of new cognitive tasks and social skills (e.g. moral reasoning, theory of mind, executive functions)
• Development of intervention programs for parents and children/teens with traumatic brain injuries

Target populations: healthy populations, traumatic brain injury, prematurity, behavioural problems, child psychiatric disorders, metabolic/genetic diseases, other neuropsychological disorders, etc.

Techniques used: MRI, fMRI, PET, DTI, eye tracking, neuropsychological assessment, longitudinal studies, etc.

My research focuses on the study of memory from the viewpoint of cognitive neuropsychology. My work has three main themes: the first examines the effect of focal brain lesions on the components of working memory, in order to better understand its organization. I am also interested in mnesic functioning in other pathologies (e.g. autism, callosotomies). A second theme of my work is characterizing working memory disorders in Alzheimer's-type dementia. In this context I am also interested in mnesic decline in normal elderly subjects. This project will eventually help identify mnesic tasks that can contribute to distinguishing between Alzheimer's-type dementia and normal aging. Lastly, the third theme is the development of tools for evaluating memory and attention that are sensitive and theory-based, for supporting the evaluation work of neuropsychology clinicians.

Dr. Brambati has a PhD in Molecular Medicine (cognitive neuropsychology profile) from the Università Vita-Salute San Raffaele in Milan, Italy (2006). She then completed post-doctoral studies at the Memory and Aging Center (University of California, San Francisco) (2006-2007), and the IUGM research centre. Today she is a researcher at the IUGM research centre (FRQ-S Junior 1) and a professor on loan to the Department of Psychology at the Université de Montréal.

Jean Gagnon, MPs, PhD, is a clinical psychologist, a neuropsychologist and an Associate Professor in the Department of Psychology at the Université de Montréal. His field of teaching is psychological assessment and personality theories. He is a full member of the Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal (CRIR) at the Centre de recherche en neuropsychologie et cognition (CERNEC).

My current research mainly concerns the cognitive and cerebral effects of different pediatric diseases and syndromes, such as epilepsy, infantile spasms, tuberous sclerosis complex (TSC), prematurity and congenital cardiac anomalies. In the laboratory, I use neuropsychological assessment and neuroimaging (optical imaging (NIRS), electroencephalography) and magnetoencephalography (MEG)) to better understand these pathologies and their impact on brain development, identify predictive markers for certain related disorders or developmental prognostics and develop pre-surgical assessment techniques suitable for use with these populations.

My research program is aimed at achieving a better understanding of normal and atypical neuropsychological development among children and teenagers. More specifically, it aims to:

• Develop and validate assessment and intervention methods for children with neurodevelopmental disorders, in particular attention deficit and learning disorders (dyslexia, dyscalculia)
• Develop and validate analytical and interpretation methods for neuropsychological data
• Model cognitive processes by means of artificial neuronal networks.

My research program is aimed at improving our understanding of the influence of music on cognition and health in both the non-clinical population and among people with neurological disorders or mental health problems. In particular, I am interested in the effect of musical moods (e.g. relaxing, stimulating) on the emotional state and on cognition (e.g. the executive functions). For instance, my research focuses on examining the impact of background music on cognition and on developing musical activities to reduce stress. My research is supported by the SSHRC.

As adults we are often amazed by how quickly and easily children learn. There are many factors influencing child development. My research program is aimed at better understanding the cerebral mechanisms involved in learning processes in children and infants.

• Study of cerebral mechanisms for learning in healthy children.
• Links with normal brain development, sleep/wake cycles, nutrition, family environment, self-regulation by children, etc.

Second, I am interested in the pathologies that sometimes occur at key moments in child development and can be harmful to cerebral, cognitive and emotional development. For instance, I am studying the effects of epilepsy caused by a developmental lesion and epilepsy with no apparent cause.

Investigation methods: neuroimaging (structural and functional), electrophysiology (EEG/MEG), behaviour (eye tracking, neuropsychological tests).

A few objectives of our research at our electrophysiology and traumatic brain injury impact study laboratory (CRLB-CRIR and CERNEC):

• The use of visual and cognitive electrophysiology and neuropsychological tests to objectify alterations in brain function and means of recovery after a traumatic brain injury (TBI)
• The study of the effectiveness of cognitive and rehabilitation interventions and the links between brain function, symptomatology and some indicators of post-TBI development, such as ability to work and quality of life