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Expert in: Cortico-striatal and cortico-cerebellar systems and learning

Doyon, Julien

DOYON, Julien

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Study of the behavioural conditions that determine the learning of motor skills and neurofunctional plasticity characterizing this type of procedural memory in adult humans, using experimental approaches involving psychophysical and psychopharmacological methods on young or elderly subjects, studies of clinical populations (e.g. Parkinson's disease or brain damage) and some imaging techniques (e.g.: positron-emission tomography [PET] and functional magnetic resonance imaging [fMRI]) in healthy subjects and neurological patients.

Exploration of the role of the simple passage of time and of sleep (nighttime and daytime) in consolidating two types of motor learning, and identification of the neuroanatomical substrates underlying the consolidation of these types of memory.

Differentiation, using neuroimaging and methods of analyzing connectivity between networks in co-activated regions, of the contribution of cerebral structures forming cortico-striatal (CS) and cortico-cerebellar (CC) circuits, and the dynamics of the neurofunctional changes involving these two cortico-subcortical systems in the different stages of learning and recalling a motor sequence or motor adaptation.

Comparative study of the neurofunctional plasticity observed during the physical and mental practice of a sequence of movements, and identification of the neuronal networks characteristic of subjects with good abilities to use IM and those revealed when visual images are activated versus kinesthetic sensations of movements.


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